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26 Jan 2021
BMRC
Institute of Molecular and Cell Biology
A genome-scale CRISPR screen reveals factors regulating Wnt-dependent renewal of mouse gastric epithelial cells
Kazuhiro Murakami,
Yumi Terakado,
Kikue Saito,
Yoshie Jomen,
Haruna Takeda,
Masanobu Oshima,
Nick Barker
Proceedings of the National Academy of Sciences
26 Jan 2021
BMRC
Institute of Molecular and Cell Biology
A constant pool of Lgr5+ intestinal stem cells is required for intestinal homeostasis
Si Hui Tan,
Phyllis Phuah,
Liang Thing Tan,
Swathi Yada,
Jasmine Goh,
Lucian B. Tomaz,
Magdalene Chua,
Esther Wong,
Bernett Lee,
Nick Barker
Cell Reports
5 Feb 2020
BMRC
Institute of Medical Biology
AQP5 enriches for stem cells and cancer origins in the distal stomach
Si Hui Tan,
Yada Swathi,
Shawna Tan,
Jasmine Goh,
Ryo Seishima,
Kazuhiro Murakami,
Masanobu Oshima,
Toshikatsu Tsuji,
Phyllis Phuah,
Liang Thing Tan,
Esther Wong,
Aliya Fatehullah,
Taotao Sheng,
Shamaine Wei Ting Ho,
Heike I. Grabsch,
Supriya Srivastava,
Ming Teh,
Simon L. I. J. Denil,
Seri Mustafah,
Patrick Tan,
Asim Shabbir,
Jimmy So,
Khay Guan Yeoh,
Nick Barker
Nature
8 Jul 2019
BMRC
Institute of Medical Biology
The Function of Lgr5+ Cells in the Gastric Antrum Does Not Require Fzd7 or Myc In Vivo
Dustin Flanagan,
Nick Barker,
Matthias Ernst,
Elizabeth Vincan,
Toby Phesse
Biomedicines
17 Jun 2019
BMRC
Institute of Medical Biology
Distinct localization of mature hgf from its precursor form in developing and repairing the stomach
Nawaphat Jangphattananont,
Hiroki Sato,
Ryu Imamura,
Katsuya Sakai,
Yumi Terakado,
Kazuhiro Murakami,
Nick Barker,
Hiroko Oshima,
Masanobu Oshima,
Junichi Takagi,
Yukinari Kato,
Seiji Yano,
Kunio Matsumoto
International Journal of Molecular Sciences
28 May 2019
BMRC
Institute of Medical Biology
Bortezomib Stabilizes and Activates p53 in Proliferative Compartments of Both Normal and Tumor Tissues In Vivo
Nick Barker,
Shawn Hoon,
Yuezhen Xue,
Pingping He,
Teena Thakur,
Shifana Raja Abdeen,
Priadarsini Maruthappan,
Farid J. Ghadessy,
David P. Lane
Cancer Research
8 Jan 2019
BMRC
Institute of Medical Biology
Frizzled-7 is required for Wnt signaling in gastric tumors with and without APC mutations
Dustin J. Flanagan,
Nick Barker,
Natasha S. Di Costanzo,
Elizabeth A. Mason,
Austin Gurney,
Valerie S. Meniel,
Sarah Koushyar,
Chloe R. Austin,
Matthias Ernst,
Helen B. Pearson,
Alex Boussioutas,
Hans Clevers,
Toby J. Phesse,
Elizabeth Vincan
Cancer Research
21 Feb 2018
BMRC
Institute of Medical Biology
Recent Advances in Lgr5+ Stem Cell Research
Carly Leung,
Si Hui Tan,
Nick Barker
Trends in Cell Biology
8 Jan 2018
BMRC
Institute of Medical Biology
Chapter Two - Wnt Signaling in Adult Epithelial Stem Cells and Cancer
Si Hui Tan,
Nick Barker
Progress in Molecular Biology and Translational Science
2 Aug 2017
BMRC
Institute of Medical Biology
Loss of the Wnt receptor frizzled 7 in the mouse gastric epithelium is deleterious and triggers rapid repopulation in vivo
Dustin J. Flanagan,
Nick Barker,
Cameron Nowell,
Hans Clevers,
Matthias Ernst,
Toby J. Phesse,
Elizabeth Vincan
Disease Models & Mechanisms
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