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16 Oct 2015
BMRC
Bioprocessing Technology Institute
Inactivation of GDP-fucose transporter gene (Slc35c1) in CHO cells by ZFNs, TALENs and CRISPR-Cas9 for production of fucose-free antibodies
Kah Fai Chan,
Wahyu Shahreel,
Corrine Wan,
Gavin Teo,
Noor Hayati,
Shi Jie Tay,
Wen Han Tong,
Yuansheng Yang,
Pauline M. Rudd,
Peiqing Zhang,
Zhiwei Song
Biotechnology Journal
11 Mar 2015
BMRC
Bioprocessing Technology Institute
Cleavage efficient 2A peptides for high level monoclonal antibody expression in CHO cells
Jake Chng,
Tianhua Wang,
Rui Nian,
Ally Lau,
Kong Meng Hoi,
Steven C. L. Ho,
Peter Gagnon,
Xuezhi Bi,
Yuansheng Yang
mAbs
4 Mar 2015
BMRC
Bioprocessing Technology Institute
Heat shock protein 27 overexpression in CHO cells modulates apoptosis pathways and delays activation of caspases to improve recombinant monoclonal antibody titre in fed‐batch bioreactors
Janice G. L. Tan,
Yih Yean Lee,
Tianhua Wang,
Miranda G. S. Yap,
Tin Wee Tan,
Say Kong Ng
Biotechnology Journal
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