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18 May 2020
BMRC
Institute of Molecular and Cell Biology
BCL-xL/BCL2L1 is a critical anti-apoptotic protein that promotes the survival of differentiating pancreatic cells from human pluripotent stem cells
Larry Sai Weng Loo,
Andreas Alvin Purnomo Soetedjo,
Hwee Hui Lau,
Natasha Hui Jin Ng,
Soumita Ghosh,
Linh Nguyen,
Vidhya Gomathi Krishnan,
Hyungwon Choi,
Xavier Roca,
Shawn Hoon,
Adrian Kee Keong Teo
Cell Death & Disease
3 Dec 2019
BMRC
p53 Laboratory
Transmembrane signaling on a protocell: creation of receptor-enzyme chimeras for immunodetection of specific antibodies and antigens
Jiulong Su,
Tetsuya Kitaguchi,
Yuki Ohmuro-Matsuyama,
Theresa Seah,
Farid J. Ghadessy,
Shawn Hoon,
Hiroshi Ueda
Scientific Reports
10 Jun 2019
BMRC
Bioinformatics Institute
Chemogenomic profiling in yeast reveals antifungal mode-of-action of polyene macrolactam auroramycin
Jin Huei Wong,
Mohammad Alfatah,
Kiat Whye Kong,
Shawn Hoon,
Wan Lin Yeo,
Kuan Chieh Ching,
Corinna Jie Hui Goh,
Mingzi M. Zhang,
Yee Hwee Lim,
Fong Tian Wong,
Prakash Arumugam
PLOS ONE
28 May 2019
BMRC
Institute of Medical Biology
Bortezomib Stabilizes and Activates p53 in Proliferative Compartments of Both Normal and Tumor Tissues In Vivo
Nick Barker,
Shawn Hoon,
Yuezhen Xue,
Pingping He,
Teena Thakur,
Shifana Raja Abdeen,
Priadarsini Maruthappan,
Farid J. Ghadessy,
David P. Lane
Cancer Research
26 May 2019
BMRC
Institute of Molecular and Cell Biology
HNF4A Haploinsufficiency in MODY1 Abrogates Liver and Pancreas Differentiation from Patient-Derived Induced Pluripotent Stem Cells
Natasha Hui Jin Ng,
Joanita Binte Jasmen,
Chang Siang Lim,
Hwee Hui Lau,
Vidhya Gomathi Krishnan,
Juned Kadiwala,
Rohit N. Kulkarni,
Helge Ræder,
Ludovic Vallier,
Shawn Hoon,
Adrian Kee Keong Teo
iScience
15 May 2019
BMRC
Singapore Institute of Food and Biotechnology Innovation
Characterization of Cas proteins for CRISPR‐Cas editing in streptomycetes
Wan Lin Yeo,
Elena Heng,
Lee Ling Tan,
Yi Wee Lim,
Yee Hwee Lim,
Shawn Hoon,
Huimin Zhao,
Mingzi Zhang,
Fong Tian Wong
Biotechnology and Bioengineering
15 Apr 2019
BMRC
Bioinformatics Institute
Chemical-genetic interaction landscape of mono-(2-ethylhexyl)-phthalate using chemogenomic profiling in yeast
Mohammad Alfatah,
Jin Huei Wong,
Kiat Whye Kong,
Felix Utama,
Shawn Hoon,
Prakash Arumugam
Chemosphere
25 May 2018
BMRC
Singapore Institute of Food and Biotechnology Innovation
Auroramycin: A Potent Antibiotic from Streptomyces roseosporus by CRISPR‐Cas9 Activation
Yee Hwee Lim,
Fong Tian Wong,
Wan Lin Yeo,
Kuan Chieh Ching,
Yi Wee Lim,
Elena Heng,
Shuwen Chen,
De‐Juin Tsai,
Tsai‐Ling Lauderdale,
Kak‐Shan Shia,
Ying Swan Ho,
Shawn Hoon,
Ee Lui Ang,
Mingzi Zhang,
Huimin Zhao
ChemBioChem
9 Mar 2018
Others
Experimental Drug Development Centre
Structure-activity relationship studies of ultra-short peptides with potent activities against fluconazole-resistant Candida albicans
Shawn Hoon,
Siew Mei Samantha Ng,
Jia Mao Yap,
Qiu Ying Lau,
Fui Mee Ng,
Esther Ong,
Timothy Barkham,
Jeanette Teo,
Alfatah Mohammad,
Kiat Whye Kong,
Prakash Arumugam,
Jeffrey Hill,
Brian Chia
European Journal of Medicinal Chemistry
2 Apr 2015
BMRC
Institute of Medical Biology
PDX1 Binds and Represses Hepatic Genes to Ensure Robust Pancreatic Commitment in Differentiating Human Embryonic Stem Cells
Christopher V.E. Wright,
Norris Ray Dunn,
Adrian Kee Keong Teo,
Norihiro Tsuneyoshi,
Shawn Hoon,
Ee Kim Tan,
Lawrence W. Stanton
Stem Cell Reports
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